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An anti-TROP2 monoclonal antibody TrMab-6 exerts antitumor activity in breast cancer mouse xenograft models

Trophoblast cell surface antigen 2 (TROP2), reported to be overexpressed in several types of cancer, is involved in cell proliferation, invasion, metastasis, and poor prognosis of many types of cancer. Previously, a highly sensitive anti-TROP2 monoclonal antibody (clone TrMab-6; mouse IgG(2b), κ) wa...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomohiro, Ohishi, Tomokazu, Asano, Teizo, Takei, Junko, Nanamiya, Ren, Hosono, Hideki, Sano, Masato, Harada, Hiroyuki, Kawada, Manabu, Kaneko, Mika K., Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144932/
https://www.ncbi.nlm.nih.gov/pubmed/34013368
http://dx.doi.org/10.3892/or.2021.8083