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ND-09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR-ABL signaling

Chronic myeloid leukemia (CML) accounts for approximately 15% of new adult leukemia cases. The fusion gene BCR-ABL is an important biological basis and target for CML. In the present study, a novel compound, ND-09, was developed and its inhibitory effect and mechanism of action on CML growth were ev...

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Detalles Bibliográficos
Autores principales: Liu, Yan-Hong, Zhu, Man, Lei, Pan-Pan, Pan, Xiao-Yan, Ma, Wei-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144938/
https://www.ncbi.nlm.nih.gov/pubmed/34036393
http://dx.doi.org/10.3892/or.2021.8087