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Conformational and Immunogenicity Studies of the Shigella flexneri Serogroup 6 O-Antigen: The Effect of O-Acetylation

The pathogenic bacterium Shigella is a leading cause of diarrheal disease and mortality, disproportionately affecting young children in low-income countries. The increasing prevalence of antibiotic resistance in Shigella necessitates an effective vaccine, for which the bacterial lipopolysaccharide O...

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Detalles Bibliográficos
Autores principales: Richardson, Nicole Inge, Ravenscroft, Neil, Arato, Vanessa, Oldrini, Davide, Micoli, Francesca, Kuttel, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144980/
https://www.ncbi.nlm.nih.gov/pubmed/33925465
http://dx.doi.org/10.3390/vaccines9050432