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Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus

Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone expression is present in type 2 diabetes (T2D). Recently, we demonstrated that a dysregulated mitochondrial stress response (MSR) with reduc...

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Detalles Bibliográficos
Autores principales: Wardelmann, Kristina, Rath, Michaela, Castro, José Pedro, Blümel, Sabine, Schell, Mareike, Hauffe, Robert, Schumacher, Fabian, Flore, Tanina, Ritter, Katrin, Wernitz, Andreas, Hosoi, Toru, Ozawa, Koichiro, Kleuser, Burkhard, Weiß, Jürgen, Schürmann, Annette, Kleinridders, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145035/
https://www.ncbi.nlm.nih.gov/pubmed/33946318
http://dx.doi.org/10.3390/antiox10050711