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Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus
Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone expression is present in type 2 diabetes (T2D). Recently, we demonstrated that a dysregulated mitochondrial stress response (MSR) with reduc...
Autores principales: | Wardelmann, Kristina, Rath, Michaela, Castro, José Pedro, Blümel, Sabine, Schell, Mareike, Hauffe, Robert, Schumacher, Fabian, Flore, Tanina, Ritter, Katrin, Wernitz, Andreas, Hosoi, Toru, Ozawa, Koichiro, Kleuser, Burkhard, Weiß, Jürgen, Schürmann, Annette, Kleinridders, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145035/ https://www.ncbi.nlm.nih.gov/pubmed/33946318 http://dx.doi.org/10.3390/antiox10050711 |
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