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Aminoglycosides in the Intensive Care Unit: What Is New in Population PK Modeling?

Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU patients. This is due to a large between- and within-subject variability in the aminoglycoside pharmacokinetics in this population. Objective: This...

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Detalles Bibliográficos
Autores principales: Duong, Alexandre, Simard, Chantale, Wang, Yi Le, Williamson, David, Marsot, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145041/
https://www.ncbi.nlm.nih.gov/pubmed/33946905
http://dx.doi.org/10.3390/antibiotics10050507