Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188

In the current study, the effect of poloxamer 188 on the complexation efficiency and dissolution of arbidol hydrochloride (ADL), a broad-spectrum antiviral agent, with β-cyclodextrin (β-CD) was investigated. Phase solubility studies confirmed a stoichiometry of a 1:1 ratio for both ADL:β-CD and ADL/...

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Detalles Bibliográficos
Autores principales: Anwer, Md. Khalid, Iqbal, Muzaffar, Ahmed, Mohammad Muqtader, Aldawsari, Mohammed F., Ansari, Mohd Nazam, Ezzeldin, Essam, Khalil, Nasr Y., Ali, Raisuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145073/
https://www.ncbi.nlm.nih.gov/pubmed/33926020
http://dx.doi.org/10.3390/ph14050411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145073/
https://www.ncbi.nlm.nih.gov/pubmed/33926020
http://dx.doi.org/10.3390/ph14050411

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