Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors

A novel series of ciprofloxacin hybrids comprising various heterocycle derivatives has been synthesized and structurally elucidated using (1)H NMR, (13)C NMR, and elementary analyses. Using ciprofloxacin as a reference, compounds 1–21 were screened in vitro against Gram-positive bacterial strains su...

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Detalles Bibliográficos
Autores principales: Al-Wahaibi, Lamya H., Amer, Amer A., Marzouk, Adel A., Gomaa, Hesham A. M., Youssif, Bahaa G. M., Abdelhamid, Antar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145110/
https://www.ncbi.nlm.nih.gov/pubmed/33922361
http://dx.doi.org/10.3390/ph14050399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145110/
https://www.ncbi.nlm.nih.gov/pubmed/33922361
http://dx.doi.org/10.3390/ph14050399

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