Combined Self-Nanoemulsifying and Solid Dispersion Systems Showed Enhanced Cinnarizine Release in Hypochlorhydria/Achlorhydria Dissolution Model

The study aims to design a novel combination of drug-free solid self-nanoemulsifying drug delivery systems (S-SNEDDS) + solid dispersion (SD) to enhance cinnarizine (CN) dissolution at high pH environment caused by hypochlorhydria/achlorhydria. Drug-loaded and drug-free liquid SNEDDS were solidified...

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Detalles Bibliográficos
Autores principales: Shahba, Ahmad A., Tashish, Ahmad Y., Alanazi, Fars K., Kazi, Mohsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145116/
https://www.ncbi.nlm.nih.gov/pubmed/33924928
http://dx.doi.org/10.3390/pharmaceutics13050627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145116/
https://www.ncbi.nlm.nih.gov/pubmed/33924928
http://dx.doi.org/10.3390/pharmaceutics13050627

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