Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice

An imbalance in the storage and breakdown of hepatic lipid droplet (LD) triglyceride (TAG) leads to hepatic steatosis, a defining feature of non-alcoholic fatty liver disease (NAFLD). The two primary cellular pathways regulating hepatic TAG catabolism are lipolysis, initiated by adipose triglyceride...

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Detalles Bibliográficos
Autores principales: Griffin, John D., Bejarano, Eloy, Wang, Xiang-Dong, Greenberg, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145136/
https://www.ncbi.nlm.nih.gov/pubmed/33923083
http://dx.doi.org/10.3390/cells10051016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145136/
https://www.ncbi.nlm.nih.gov/pubmed/33923083
http://dx.doi.org/10.3390/cells10051016

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