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Deletion of Mitochondrial Translocator Protein (TSPO) Gene Decreases Oxidative Retinal Pigment Epithelial Cell Death via Modulation of TRPM2 Channel

SIMPLE SUMMARY: 18 kDa mitochondrial translocator protein (TSPO) is a mitochondria protein of the cellular outer membrane in the mitochondria of several cells, including ARPE19 is TSPO. Accumulating evince indicates that the presence of TSPO participated the modulations of Ca(2+) homeostasis and mit...

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Detalles Bibliográficos
Autores principales: Özkaya, Dilek, Shu, Xinhua, Nazıroğlu, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145237/
https://www.ncbi.nlm.nih.gov/pubmed/33924902
http://dx.doi.org/10.3390/biology10050382