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Preparation of Topical Itraconazole with Enhanced Skin/Nail Permeability and In Vivo Antifungal Efficacy against Superficial Mycosis

In this study, a stable and highly skin-permeable topical delivery system for itraconazole (ITZ) was designed to provide effective treatment against superficial mycosis. Herein, ITZ was incorporated into a solution composed of ethanol, benzyl alcohol, hydrochloric acid, Transcutol P, and cyclomethic...

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Detalles Bibliográficos
Autores principales: Subedi, Laxman, Song, Seung-Yub, Jha, Saurav Kumar, Lee, Sung-Ho, Pangeni, Rudra, Koo, Kyo-Tan, Kim, Beum Joon, Cho, Seung-Sik, Park, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145258/
https://www.ncbi.nlm.nih.gov/pubmed/33925457
http://dx.doi.org/10.3390/pharmaceutics13050622