Preclinical Detection of Alpha-Synuclein Seeding Activity in the Colon of a Transgenic Mouse Model of Synucleinopathy by RT-QuIC

In synucleinopathies such as Parkinson’s disease (PD) and dementia with Lewy body (DLB), pathological alpha-synuclein (α-syn) aggregates are found in the gastrointestinal (GI) tract as well as in the brain. In this study, using real-time quaking-induced conversion (RT-QuIC), we investigated the pres...

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Detalles Bibliográficos
Autores principales: Han, Jung-Youn, Shin, Chaewon, Choi, Young Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145297/
https://www.ncbi.nlm.nih.gov/pubmed/33926043
http://dx.doi.org/10.3390/v13050759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145297/
https://www.ncbi.nlm.nih.gov/pubmed/33926043
http://dx.doi.org/10.3390/v13050759

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