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Investigating Cellular Trajectories in the Severity of COVID-19 and Their Transcriptional Programs Using Machine Learning Approaches

Single-cell RNA sequencing of the bronchoalveolar lavage fluid (BALF) samples from COVID-19 patients has enabled us to examine gene expression changes of human tissue in response to the SARS-CoV-2 virus infection. However, the underlying mechanisms of COVID-19 pathogenesis at single-cell resolution,...

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Detalles Bibliográficos
Autores principales: Jeong, Hyun-Hwan, Jia, Johnathan, Dai, Yulin, Simon, Lukas M., Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145325/
https://www.ncbi.nlm.nih.gov/pubmed/33923155
http://dx.doi.org/10.3390/genes12050635