S100P Interacts with p53 while Pentamidine Inhibits This Interaction

S100P, a small calcium-binding protein, associates with the p53 protein with micromolar affinity. It has been hypothesized that the oncogenic function of S100P may involve binding-induced inactivation of p53. We used (1)H-(15)N HSQC experiments and molecular modeling to study the molecular interacti...

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Detalles Bibliográficos
Autores principales: Katte, Revansiddha H., Dowarha, Deepu, Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145327/
https://www.ncbi.nlm.nih.gov/pubmed/33923162
http://dx.doi.org/10.3390/biom11050634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145327/
https://www.ncbi.nlm.nih.gov/pubmed/33923162
http://dx.doi.org/10.3390/biom11050634

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