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S100P Interacts with p53 while Pentamidine Inhibits This Interaction
S100P, a small calcium-binding protein, associates with the p53 protein with micromolar affinity. It has been hypothesized that the oncogenic function of S100P may involve binding-induced inactivation of p53. We used (1)H-(15)N HSQC experiments and molecular modeling to study the molecular interacti...
Autores principales: | Katte, Revansiddha H., Dowarha, Deepu, Chou, Ruey-Hwang, Yu, Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145327/ https://www.ncbi.nlm.nih.gov/pubmed/33923162 http://dx.doi.org/10.3390/biom11050634 |
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