Optimized Synthesis of New N-Mustards Based on 2-Mercaptobenzoxazole Derivatives with Antitumor Activity

New di-(β-chloroethyl)-amides of some acids derived from 2-mercaptobenzoxazole were prepared by reaction of the corresponding pivalic mixed anhydrides with di-(β-chloroethyl)-amine. A study regarding the optimization of the chemical reactions was made for the case of di-(β-chloroethyl)-amines. The q...

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Detalles Bibliográficos
Autores principales: Cheptea, Corina, Sunel, Valeriu, Morosanu, Ana Cezarina, Dimitriu, Dan Gheorghe, Dulcescu-Oprea, Mihaela Maria, Angheluta, Mihai-Daniel, Miron, Mihaela, Nechifor, Cristina Delia, Dorohoi, Dana Ortansa, Malancus, Razvan Nicolae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145375/
https://www.ncbi.nlm.nih.gov/pubmed/33926050
http://dx.doi.org/10.3390/biomedicines9050476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145375/
https://www.ncbi.nlm.nih.gov/pubmed/33926050
http://dx.doi.org/10.3390/biomedicines9050476

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