Zero Echo Time (17)O-MRI Reveals Decreased Cerebral Metabolic Rate of Oxygen Consumption in a Murine Model of Amyloidosis

The cerebral metabolic rate of oxygen consumption (CMRO(2)) is a key metric to investigate the mechanisms involved in neurodegeneration in animal models and evaluate potential new therapies. CMRO(2) can be measured by direct (17)O magnetic resonance imaging ((17)O-MRI) of H(2)(17)O signal changes du...

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Detalles Bibliográficos
Autores principales: Baligand, Celine, Barret, Olivier, Tourais, Amélie, Pérot, Jean-Baptiste, Thenadey, Didier, Petit, Fanny, Liot, Géraldine, Gaillard, Marie-Claude, Flament, Julien, Dhenain, Marc, Valette, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145383/
https://www.ncbi.nlm.nih.gov/pubmed/33922384
http://dx.doi.org/10.3390/metabo11050263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145383/
https://www.ncbi.nlm.nih.gov/pubmed/33922384
http://dx.doi.org/10.3390/metabo11050263

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