Sustained Surface ICAM-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated NOD2 Mutations

Objectives: Blau syndrome is a distinct class of autoinflammatory syndrome presenting with early-onset systemic granulomatosis. Blau syndrome-causing NOD2 mutations located in the central nucleotide-oligomerization domain induce ligand-independent basal NF-κB activation in an in vitro reporter assay...

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Detalles Bibliográficos
Autores principales: Nishiyama, Mizuho, Li, Hong-jin, Okafuji, Ikuo, Fujisawa, Akihiko, Ehara, Mizue, Kambe, Naotomo, Furukawa, Fukumi, Kanazawa, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145400/
https://www.ncbi.nlm.nih.gov/pubmed/33923123
http://dx.doi.org/10.3390/children8050335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145400/
https://www.ncbi.nlm.nih.gov/pubmed/33923123
http://dx.doi.org/10.3390/children8050335

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