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Formyl-selective deuteration of aldehydes with D(2)O via synergistic organic and photoredox catalysis

Formyl-selective deuteration of aldehydes is of high interest for labeling purposes and for optimizing properties of drug candidates. Herein, we report a mild general method for formyl-selective deuterium labeling of aldehydes with D(2)O, an inexpensive deuterium source, via a synergistic combinatio...

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Detalles Bibliográficos
Autores principales: Dong, Jianyang, Wang, Xiaochen, Wang, Zhen, Song, Hongjian, Liu, Yuxiu, Wang, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145436/
https://www.ncbi.nlm.nih.gov/pubmed/34084358
http://dx.doi.org/10.1039/c9sc05132e