Drosophila O-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes

The reversible posttranslational O-GlcNAc modification of serine or threonine residues of intracellular proteins is involved in many cellular events from signaling cascades to epigenetic and transcriptional regulation. O-GlcNAcylation is a conserved nutrient-dependent process involving two enzymes,...

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Detalles Bibliográficos
Autores principales: Akan, Ilhan, Halim, Adnan, Vakhrushev, Sergey Y., Clausen, Henrik, Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145559/
https://www.ncbi.nlm.nih.gov/pubmed/33925313
http://dx.doi.org/10.3390/cells10051026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145559/
https://www.ncbi.nlm.nih.gov/pubmed/33925313
http://dx.doi.org/10.3390/cells10051026

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