Cargando…
Drosophila O-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes
The reversible posttranslational O-GlcNAc modification of serine or threonine residues of intracellular proteins is involved in many cellular events from signaling cascades to epigenetic and transcriptional regulation. O-GlcNAcylation is a conserved nutrient-dependent process involving two enzymes,...
Autores principales: | Akan, Ilhan, Halim, Adnan, Vakhrushev, Sergey Y., Clausen, Henrik, Hanover, John A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145559/ https://www.ncbi.nlm.nih.gov/pubmed/33925313 http://dx.doi.org/10.3390/cells10051026 |
Ejemplares similares
-
O-GlcNAcase contributes to cognitive function in Drosophila
por: Muha, Villo, et al.
Publicado: (2020) -
Structural and functional insight into human O-GlcNAcase
por: Roth, Christian, et al.
Publicado: (2017) -
Structural studies of a surface-entropy reduction mutant of O-GlcNAcase
por: Males, Alexandra, et al.
Publicado: (2019) -
Differential Effects of an O-GlcNAcase Inhibitor on Tau Phosphorylation
por: Yu, Yang, et al.
Publicado: (2012) -
Synergy of Peptide and Sugar in O-GlcNAcase Substrate Recognition
por: Schimpl, Marianne, et al.
Publicado: (2012)