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Pneumolysin Is Responsible for Differential Gene Expression and Modifications in the Epigenetic Landscape of Primary Monocyte Derived Macrophages

Epigenetic modifications regulate gene expression in the host response to a diverse range of pathogens. The extent and consequences of epigenetic modification during macrophage responses to Streptococcus pneumoniae, and the role of pneumolysin, a key Streptococcus pneumoniae virulence factor, in inf...

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Detalles Bibliográficos
Autores principales: Cole, Joby, Angyal, Adrienn, Emes, Richard D., Mitchell, Tim John, Dickman, Mark J., Dockrell, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145618/
https://www.ncbi.nlm.nih.gov/pubmed/34046027
http://dx.doi.org/10.3389/fimmu.2021.573266