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Perspectives on Non-BLT Humanized Mouse Models for Studying HIV Pathogenesis and Therapy

A variety of humanized mice, which are reconstituted only with human hematopoietic stem cells (HSC) or with fetal thymus and HSCs, have been developed and widely utilized as in vivo animal models of HIV-1 infection. The models represent some aspects of HIV-mediated pathogenesis in humans and are use...

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Detalles Bibliográficos
Autores principales: Terahara, Kazutaka, Iwabuchi, Ryutaro, Tsunetsugu-Yokota, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145733/
https://www.ncbi.nlm.nih.gov/pubmed/33924786
http://dx.doi.org/10.3390/v13050776