CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats

Clasmatodendrosis is an autophagic astroglial death showing extensive swollen cell bodies with vacuoles and disintegrated/beaded processes. This astroglial degeneration is closely relevant to the synchronous epileptiform discharges. However, the underlying molecular mechanisms and the roles of clasm...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145743/
https://www.ncbi.nlm.nih.gov/pubmed/33922531
http://dx.doi.org/10.3390/antiox10050655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145743/
https://www.ncbi.nlm.nih.gov/pubmed/33922531
http://dx.doi.org/10.3390/antiox10050655

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