Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses

BACKGROUND: The interleukin (IL)-1 pathway is primarily associated with innate immunological defense and plays a major role in the induction and regulation of inflammation. Both common and rare genetic variation in this pathway underlies various inflammation-mediated diseases, but the role of rare v...

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Detalles Bibliográficos
Autores principales: van Deuren, Rosanne C., Arts, Peer, Cavalli, Giulio, Jaeger, Martin, Steehouwer, Marloes, van de Vorst, Maartje, Gilissen, Christian, Joosten, Leo A. B., Dinarello, Charles A., Mhlanga, Musa M., Kumar, Vinod, Netea, Mihai G., van de Veerdonk, Frank L., Hoischen, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145796/
https://www.ncbi.nlm.nih.gov/pubmed/34034819
http://dx.doi.org/10.1186/s13073-021-00907-w

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