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Comparative evaluation of full-length isoform quantification from RNA-Seq

BACKGROUND: Full-length isoform quantification from RNA-Seq is a key goal in transcriptomics analyses and has been an area of active development since the beginning. The fundamental difficulty stems from the fact that RNA transcripts are long, while RNA-Seq reads are short. RESULTS: Here we use simu...

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Detalles Bibliográficos
Autores principales: Sarantopoulou, Dimitra, Brooks, Thomas G., Nayak, Soumyashant, Mrčela, Antonijo, Lahens, Nicholas F., Grant, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145802/
https://www.ncbi.nlm.nih.gov/pubmed/34034652
http://dx.doi.org/10.1186/s12859-021-04198-1