Hyperpolarized (13)C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

This study uses dynamic hyperpolarized [1-(13)C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer models. The apparent conversion rate of pyruv...

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Detalles Bibliográficos
Autores principales: Macdonald, Erin B., Begovatz, Paul, Barton, Gregory P., Erickson-Bhatt, Sarah, Inman, David R., Cox, Benjamin L., Eliceiri, Kevin W., Strigel, Roberta M., Ponik, Suzanne M., Fain, Sean B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145849/
https://www.ncbi.nlm.nih.gov/pubmed/33925445
http://dx.doi.org/10.3390/metabo11050274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145849/
https://www.ncbi.nlm.nih.gov/pubmed/33925445
http://dx.doi.org/10.3390/metabo11050274

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