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Hyperpolarized (13)C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential
This study uses dynamic hyperpolarized [1-(13)C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer models. The apparent conversion rate of pyruv...
Autores principales: | Macdonald, Erin B., Begovatz, Paul, Barton, Gregory P., Erickson-Bhatt, Sarah, Inman, David R., Cox, Benjamin L., Eliceiri, Kevin W., Strigel, Roberta M., Ponik, Suzanne M., Fain, Sean B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145849/ https://www.ncbi.nlm.nih.gov/pubmed/33925445 http://dx.doi.org/10.3390/metabo11050274 |
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