Fucoidan from Laminaria japonica Inhibits Expression of GLUT9 and URAT1 via PI3K/Akt, JNK and NF-κB Pathways in Uric Acid-Exposed HK-2 Cells

This work aimed to investigate the effect of fucoidan (FPS) on urate transporters induced by uric acid (UA). The results showed that UA stimulated the expression of glucose transporter 9 (GLUT9) and urate transporter 1 (URAT1) in HK-2 cells, and FPS could reverse the effect. Moreover, UA could activ...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Tan, Xiaohui, Lin, Zhen, Li, Fangping, Yang, Chunyan, Zheng, Haiying, Li, Lingyu, Liu, Huazhong, Shang, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145932/
https://www.ncbi.nlm.nih.gov/pubmed/33922488
http://dx.doi.org/10.3390/md19050238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145932/
https://www.ncbi.nlm.nih.gov/pubmed/33922488
http://dx.doi.org/10.3390/md19050238

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