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Chemical Inhibitors of Dynamin Exert Differential Effects in VEGF Signaling

VEGFR2 is the main receptor and mediator of the vasculogenic and angiogenic activity of VEGF. Activated VEGFR2 internalizes through clathrin-mediated endocytosis and macropinocytosis. As dynamin is a key regulator of the clathrin pathway, chemical inhibitors of dynamin are commonly used to assess th...

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Detalles Bibliográficos
Autores principales: Basagiannis, Dimitris, Zografou, Sofia, Goula, Evangeli, Gkeka, Despoina, Kolettas, Evangelos, Christoforidis, Savvas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145957/
https://www.ncbi.nlm.nih.gov/pubmed/33922806
http://dx.doi.org/10.3390/cells10050997