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Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4
Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl(−) and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered by mutating CFTR deve...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145967/ https://www.ncbi.nlm.nih.gov/pubmed/33923029 http://dx.doi.org/10.3390/cells10051014 |