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Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl(−) and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered by mutating CFTR deve...

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Detalles Bibliográficos
Autores principales: Chen, Oliver G., Mather, Steven E., Brommel, Christian M., Hamilton, Bradley A., Ehler, Annie, Villacreses, Raul, Girgis, Reda E., Abou Alaiwa, Mahmoud, Stoltz, David A., Zabner, Joseph, Li, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145967/
https://www.ncbi.nlm.nih.gov/pubmed/33923029
http://dx.doi.org/10.3390/cells10051014