Cargando…

Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl(−) and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered by mutating CFTR deve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Oliver G., Mather, Steven E., Brommel, Christian M., Hamilton, Bradley A., Ehler, Annie, Villacreses, Raul, Girgis, Reda E., Abou Alaiwa, Mahmoud, Stoltz, David A., Zabner, Joseph, Li, Xiaopeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145967/ https://www.ncbi.nlm.nih.gov/pubmed/33923029 http://dx.doi.org/10.3390/cells10051014

Ejemplares similares

Tromethamine improves mucociliary clearance in cystic fibrosis pigs
por: Ash, Jamison J., et al.
Publicado: (2022)

Syngeneic AAV Pseudo-particles Potentiate Gene Transduction of AAV Vectors
por: Wang, Qizhao, et al.
Publicado: (2016)

Integrin α6β4 Identifies Human Distal Lung Epithelial Progenitor Cells with Potential as a Cell-Based Therapy for Cystic Fibrosis Lung Disease
por: Li, Xiaopeng, et al.
Publicado: (2013)

AAV-mediated photoreceptor transduction of the pig cone-enriched retina
por: Mussolino, C, et al.
Publicado: (2011)

Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption
por: Orlowski, Alejandro, et al.
Publicado: (2020)

Screened AAV variants permit efficient transduction access to supporting cells and hair cells
por: Hu, Xinde, et al.
Publicado: (2019)

A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System
por: Krolak, Trevor, et al.
Publicado: (2022)

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression
por: Zengel, James, et al.
Publicado: (2023)

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS
por: Kanaan, Nicholas M., et al.
Publicado: (2017)

High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing
por: Ling, Chen, et al.
Publicado: (2016)

Hair Cell Transduction Efficiency of Single- and Dual-AAV Serotypes in Adult Murine Cochleae
por: Omichi, Ryotaro, et al.
Publicado: (2020)

Transduction of Salivary Gland Acinar Cells with a Novel AAV Vector 44.9
por: Di Pasquale, Giovanni, et al.
Publicado: (2020)

Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV
por: Naeimi Kararoudi, Meisam, et al.
Publicado: (2022)

Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing
por: Thornell, Ian M., et al.
Publicado: (2018)

Polymers for Improving the In Vivo Transduction Efficiency of AAV2 Vectors
por: Moulay, Gilles, et al.
Publicado: (2010)

Role of Essential Metal Ions in AAV Vector-Mediated Transduction
por: Rambhai, Himanshu K., et al.
Publicado: (2020)

Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction
por: Madrakhimov, Sanjar Batirovich, et al.
Publicado: (2020)

An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction
por: Santoscoy, Miguel C., et al.
Publicado: (2023)

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury
por: Nickells, Robert W., et al.
Publicado: (2017)

Preferred transduction with AAV8 and AAV9 via thalamic administration in the MPS IIIB model: A comparison of four rAAV serotypes
por: Gilkes, J.A., et al.
Publicado: (2015)

Transduction optimization of AAV vectors for human gene therapy of glaucoma and their reversed cell entry characteristics
por: Rodriguez-Estevez, Laura, et al.
Publicado: (2019)

Directed evolution of AAV accounting for long-term and enhanced transduction of cardiovascular endothelial cells in vivo
por: Liu, Y.B., et al.
Publicado: (2021)

Robust Long-term Transduction of Common Marmoset Neuromuscular Tissue With rAAV1 and rAAV9
por: Okada, Hironori, et al.
Publicado: (2013)

Direct Interaction of Human Serum Proteins with AAV Virions to Enhance AAV Transduction: Immediate Impact on Clinical Applications
por: Wang, Mei, et al.
Publicado: (2016)

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
por: Chakrabarty, Paramita, et al.
Publicado: (2013)

Standard screening methods underreport AAV-mediated transduction and gene editing
por: Lang, Jonathan F., et al.
Publicado: (2019)

FXYD3 facilitates Na(+) and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase
por: Cano Portillo, Camilo, et al.
Publicado: (2022)

Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing
por: Yang, Hua, et al.
Publicado: (2020)

CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain
por: Mathiesen, Sophie N., et al.
Publicado: (2020)

Efficient gene transduction in pigs and macaques with the engineered AAV vector AAV.GT5 for hemophilia B gene therapy
por: Kashiwakura, Yuji, et al.
Publicado: (2023)

Development of optimized AAV3 serotype vectors: Mechanism of high-efficiency transduction of human liver cancer cells
por: Cheng, Binbin, et al.
Publicado: (2011)

Red Blood Cell Anchoring Enables Targeted Transduction and Re‐Administration of AAV‐Mediated Gene Therapy
por: Zhao, Zongmin, et al.
Publicado: (2022)

AAV-Mediated Transduction and Targeting of Retinal Bipolar Cells with Improved mGluR6 Promoters in Rodents and Primates
por: Lu, Q, et al.
Publicado: (2016)

Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines
por: Ryals, Renee C., et al.
Publicado: (2011)

Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly
por: Viney, Lydia, et al.
Publicado: (2021)

Peptide Ligands Incorporated into the Threefold Spike Capsid Domain to Re-Direct Gene Transduction of AAV8 and AAV9 In Vivo
por: Michelfelder, Stefan, et al.
Publicado: (2011)

Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2
por: Cehajic-Kapetanovic, Jasmina, et al.
Publicado: (2011)

Experimental Variables that Affect Human Hepatocyte AAV Transduction in Liver Chimeric Mice
por: Zou, Chenhui, et al.
Publicado: (2020)

AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear
por: Ivanchenko, Maryna V., et al.
Publicado: (2021)

A Single Cisterna Magna Injection of AAV Leads to Binaural Transduction in Mice
por: Blanc, Fabian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0bu8t98qhtfrfni03ct5kedun0