Two New (β)N-Alkanoyl-5-Hydroxytryptamides with Relevant Antinociceptive Activity

In this work, we describe a new route for the synthesis and the antinociceptive effects of two new (β)N-alkanoyl-5-hydroxytryptamides (named C(20:0)-5HT and C(22:0)-5HT). The antinociceptive activities were evaluated using well-known models of thermal-induced (reaction to a heated plate, the hot pla...

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Detalles Bibliográficos
Autores principales: Amorim, Jorge Luis, Lima, Fernanda Alves, Brand, Ana Laura Macedo, Cunha, Silvio, Rezende, Claudia Moraes, Fernandes, Patricia Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146016/
https://www.ncbi.nlm.nih.gov/pubmed/33922159
http://dx.doi.org/10.3390/biomedicines9050455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146016/
https://www.ncbi.nlm.nih.gov/pubmed/33922159
http://dx.doi.org/10.3390/biomedicines9050455

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