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Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo

2,3-Dehydrosilybin (DHS) was previously shown to chelate and reduce both copper and iron ions. In this study, similar experiments with 2,3-dehydrosilychristin (DHSCH) showed that this congener of DHS also chelates and reduces both metals. Statistical analysis pointed to some differences between both...

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Detalles Bibliográficos
Autores principales: Lomozová, Zuzana, Tvrdý, Václav, Hrubša, Marcel, Catapano, Maria Carmen, Macáková, Kateřina, Biedermann, David, Kučera, Radim, Křen, Vladimír, Mladěnka, Přemysl, Valentová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146032/
https://www.ncbi.nlm.nih.gov/pubmed/33925336
http://dx.doi.org/10.3390/antiox10050679