Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressive Function in Human Primary Activated Thymocytes Ex Vivo

Regulatory T cells (Tregs), which are characterized by the expression of the transcription factor forkhead box P3 (FOXP3), are the main immune cells that induce tolerance and are regulators of immune homeostasis. Natural Treg cells (nTregs), described as CD4(+)CD25(+)FOXP3(+), are generated in the t...

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Detalles Bibliográficos
Autores principales: Gallego-Valle, Jorge, Gil-Manso, Sergio, Pita, Ana, Bernaldo-de-Quirós, Esther, López-Esteban, Rocío, Martínez-Bonet, Marta, Pérez-Fernández, Verónica Astrid, Pérez-Caballero, Ramón, Pardo, Carlos, Gil-Jaurena, Juan-Miguel, Correa-Rocha, Rafael, Pion, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146103/
https://www.ncbi.nlm.nih.gov/pubmed/33922629
http://dx.doi.org/10.3390/biomedicines9050461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146103/
https://www.ncbi.nlm.nih.gov/pubmed/33922629
http://dx.doi.org/10.3390/biomedicines9050461

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