Loss of park7 activity has differential effects on expression of iron responsive element (IRE) gene sets in the brain transcriptome in a zebrafish model of Parkinson’s disease

Mutation of the gene PARK7 (DJ1) causes monogenic autosomal recessive Parkinson’s disease (PD) in humans. Subsequent alterations of PARK7 protein function lead to mitochondrial dysfunction, a major element in PD pathology. Homozygous mutants for the PARK7-orthologous genes in zebrafish, park7, show...

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Detalles Bibliográficos
Autores principales: Chin, Hui Yung, Lardelli, Michael, Collins-Praino, Lyndsey, Barthelson, Karissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146209/
https://www.ncbi.nlm.nih.gov/pubmed/34030724
http://dx.doi.org/10.1186/s13041-021-00792-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146209/
https://www.ncbi.nlm.nih.gov/pubmed/34030724
http://dx.doi.org/10.1186/s13041-021-00792-9

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