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Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides

Mimicking bacterial DNA, synthetic CpG-containing oligodeoxyribonucleotides (CpG-ODNs) have a powerful immunomodulatory potential. Their practical application is mainly associated with the production of vaccines, where they are used as adjuvants, as well as in local antimicrobial therapy. CpG-ODNs a...

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Detalles Bibliográficos
Autores principales: Golenkina, Ekaterina A., Galkina, Svetlana I., Dolinnaya, Nina G., Arifulin, Evgenii A., Romanova, Yulia M., Sud’ina, Galina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146577/
https://www.ncbi.nlm.nih.gov/pubmed/33924760
http://dx.doi.org/10.3390/pathogens10050530