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Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides
Mimicking bacterial DNA, synthetic CpG-containing oligodeoxyribonucleotides (CpG-ODNs) have a powerful immunomodulatory potential. Their practical application is mainly associated with the production of vaccines, where they are used as adjuvants, as well as in local antimicrobial therapy. CpG-ODNs a...
Autores principales: | Golenkina, Ekaterina A., Galkina, Svetlana I., Dolinnaya, Nina G., Arifulin, Evgenii A., Romanova, Yulia M., Sud’ina, Galina F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146577/ https://www.ncbi.nlm.nih.gov/pubmed/33924760 http://dx.doi.org/10.3390/pathogens10050530 |
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