Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells

Triple negative breast cancer (TNBC) is observed in ~15% of breast cancers and results in poor survival and increased distant metastases. Within the tumor are present a small portion of cancer stem cells that drive tumorigenesis and metastasis. In this study, we aimed to elucidate whether the two na...

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Detalles Bibliográficos
Autores principales: Ramamoorthy, Prabhu, Dandawate, Prasad, Jensen, Roy A., Anant, Shrikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146582/
https://www.ncbi.nlm.nih.gov/pubmed/33924995
http://dx.doi.org/10.3390/biomedicines9050482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146582/
https://www.ncbi.nlm.nih.gov/pubmed/33924995
http://dx.doi.org/10.3390/biomedicines9050482

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