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Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells
Triple negative breast cancer (TNBC) is observed in ~15% of breast cancers and results in poor survival and increased distant metastases. Within the tumor are present a small portion of cancer stem cells that drive tumorigenesis and metastasis. In this study, we aimed to elucidate whether the two na...
Autores principales: | Ramamoorthy, Prabhu, Dandawate, Prasad, Jensen, Roy A., Anant, Shrikant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146582/ https://www.ncbi.nlm.nih.gov/pubmed/33924995 http://dx.doi.org/10.3390/biomedicines9050482 |
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