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Comprehensive machine-learning-based analysis of microRNA–target interactions reveals variable transferability of interaction rules across species

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally via base-pairing with complementary sequences on messenger RNAs (mRNAs). Due to the technical challenges involved in the application of high-throughput experimental methods, datasets of dire...

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Detalles Bibliográficos
Autores principales: Ben Or, Gilad, Veksler-Lublinsky, Isana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146624/
https://www.ncbi.nlm.nih.gov/pubmed/34030625
http://dx.doi.org/10.1186/s12859-021-04164-x