Green Production of Cladribine by Using Immobilized 2′-Deoxyribosyltransferase from Lactobacillus delbrueckii Stabilized through a Double Covalent/Entrapment Technology

Nowadays, enzyme-mediated processes offer an eco-friendly and efficient alternative to the traditional multistep and environmentally harmful chemical processes. Herein we report the enzymatic synthesis of cladribine by a novel 2′-deoxyribosyltransferase (NDT)-based combined biocatalyst. To this end,...

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Detalles Bibliográficos
Autores principales: Rivero, Cintia Wanda, García, Natalia Soledad, Fernández-Lucas, Jesús, Betancor, Lorena, Romanelli, Gustavo Pablo, Trelles, Jorge Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146660/
https://www.ncbi.nlm.nih.gov/pubmed/33947162
http://dx.doi.org/10.3390/biom11050657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146660/
https://www.ncbi.nlm.nih.gov/pubmed/33947162
http://dx.doi.org/10.3390/biom11050657

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