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Green Production of Cladribine by Using Immobilized 2′-Deoxyribosyltransferase from Lactobacillus delbrueckii Stabilized through a Double Covalent/Entrapment Technology

Nowadays, enzyme-mediated processes offer an eco-friendly and efficient alternative to the traditional multistep and environmentally harmful chemical processes. Herein we report the enzymatic synthesis of cladribine by a novel 2′-deoxyribosyltransferase (NDT)-based combined biocatalyst. To this end,...

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Detalles Bibliográficos
Autores principales:	Rivero, Cintia Wanda, García, Natalia Soledad, Fernández-Lucas, Jesús, Betancor, Lorena, Romanelli, Gustavo Pablo, Trelles, Jorge Abel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146660/ https://www.ncbi.nlm.nih.gov/pubmed/33947162 http://dx.doi.org/10.3390/biom11050657

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