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Single-molecule nanopore sensing of actin dynamics and drug binding

Actin is a key protein in the dynamic processes within the eukaryotic cell. To date, methods exploring the molecular state of actin are limited to insights gained from structural approaches, providing a snapshot of protein folding, or methods that require chemical modifications compromising actin mo...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyi, Wilkinson, Mark D., Lin, Xiaoyan, Ren, Ren, Willison, Keith R., Ivanov, Aleksandar P., Baum, Jake, Edel, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146688/
https://www.ncbi.nlm.nih.gov/pubmed/34084351
http://dx.doi.org/10.1039/c9sc05710b