Imbalance between Expression of FOXC2 and Its lncRNA in Lymphedema-Distichiasis Caused by Frameshift Mutations

Forkhead-box C2 (FOXC2) is a transcription factor involved in lymphatic system development. FOXC2 mutations cause Lymphedema-distichiasis syndrome (LD). Recently, a natural antisense was identified, called lncRNA FOXC2-AS1, which increases FOXC2 mRNA stability. No studies have evaluated FOXC2 and FO...

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Detalles Bibliográficos
Autores principales: Missaglia, Sara, Tavian, Daniela, Michelini, Sandro, Maltese, Paolo Enrico, Bonanomi, Andrea, Bertelli, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146868/
https://www.ncbi.nlm.nih.gov/pubmed/33925370
http://dx.doi.org/10.3390/genes12050650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146868/
https://www.ncbi.nlm.nih.gov/pubmed/33925370
http://dx.doi.org/10.3390/genes12050650

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