Correlated Motions of Conserved Polar Motifs Lay out a Plausible Mechanism of G Protein-Coupled Receptor Activation

Recent advancements in the field of experimental structural biology have provided high-resolution structures of active and inactive state G protein-coupled receptors (GPCRs), a highly important pharmaceutical target family, but the process of transition between these states is poorly understood. Acc...

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Detalles Bibliográficos
Autores principales: Mitra, Argha, Sarkar, Arijit, Szabó, Márton Richárd, Borics, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146931/
https://www.ncbi.nlm.nih.gov/pubmed/33946214
http://dx.doi.org/10.3390/biom11050670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146931/
https://www.ncbi.nlm.nih.gov/pubmed/33946214
http://dx.doi.org/10.3390/biom11050670

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