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Correlated Motions of Conserved Polar Motifs Lay out a Plausible Mechanism of G Protein-Coupled Receptor Activation
Recent advancements in the field of experimental structural biology have provided high-resolution structures of active and inactive state G protein-coupled receptors (GPCRs), a highly important pharmaceutical target family, but the process of transition between these states is poorly understood. Acc...
Autores principales: | Mitra, Argha, Sarkar, Arijit, Szabó, Márton Richárd, Borics, Attila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146931/ https://www.ncbi.nlm.nih.gov/pubmed/33946214 http://dx.doi.org/10.3390/biom11050670 |
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