In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis—Technical Aspects and Model Interpretation

Ketogenesis occurs in liver mitochondria where acetyl-CoA molecules, derived from lipid oxidation, are condensed into acetoacetate (AcAc) and reduced to β-hydroxybutyrate (BHB). During carbohydrate scarcity, these two ketones are released into circulation at high rates and used as oxidative fuels in...

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Detalles Bibliográficos
Autores principales: Deja, Stanislaw, Kucejova, Blanka, Fu, Xiaorong, Browning, Jeffrey D., Young, Jamey D., Burgess, Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146959/
https://www.ncbi.nlm.nih.gov/pubmed/33924948
http://dx.doi.org/10.3390/metabo11050279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8146959/
https://www.ncbi.nlm.nih.gov/pubmed/33924948
http://dx.doi.org/10.3390/metabo11050279

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