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Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe

BACKGROUND: Drug potency is a pharmacological parameter defining dose or concentration of drug required to obtain 50% of the drug’s maximal effect. Pharmacokinetic-pharmacodynamic modelling and simulation allows estimation of potency and evaluate strategies improving treatment outcome. The objective...

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Detalles Bibliográficos
Autores principales: Ngara, Bernard, Zvada, Simbarashe, Chawana, Tariro Dianah, Nhachi, Charles Fungai Brian, Rusakaniko, Simbarashe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147021/
https://www.ncbi.nlm.nih.gov/pubmed/34030726
http://dx.doi.org/10.1186/s40360-021-00497-8